Advanced Therapeutics The RNA Riddle: Why Getting the Secondary Structure Right is Important RNA secondary structures are key in RNA virus function and evolution, and thus are potential therapeutic targets. Identifying these is challenging, but AI/ML techniques provide a promising approach.
Research Project Increasing the vehicle capacity for gene therapy Gene therapy or living drugs is one of the most exciting areas of biotechnology, and we’d like to tell you about some of the progress we’ve made in expanding the potential
case study Case Study: Boosting product confidence of a world-leading RNA therapeutics start-up CSIRO’s Transformational Bioinformatics group validates the importance of long non-coding RNAs (lncRNAs) as novel cancer therapeutics targets. The ClientAmaroq Therapeutics is a New Zealand-based biotechnology company targeting long non-coding RNAs for next
Explainer Scissors, glue or white-out? Using the CRISPR pencil-case Since the original demonstration that CRISPR-Cas9 can be used to induce targeted changes in a cell's genome, there has been an explosion of new versions and variations of different CRISPR systems. While some
Scientific publication Finding viral integrations with isling CSIRO has published a software tool to detect if and where viral DNA has integrated into the genome of its host. This helps assess the consequences of a viral infection and the safety
Scientific publication New software-guided approach streamlines genome editing capability CSIRO has developed a computational tool for a new genome editing approach that makes research and clinical applications more effective. The approach consists of a new gene editing strategy developed by the University
GenomeWeb GenomeWeb: CSIRO Develops Software to Detect Foreign DNA Without Reference Genomes CHICAGO – Bioinformaticians with the Australian e-Health Research Centre at the Commonwealth Scientific and Industrial Research Organisation have developed a computing algorithm to detect foreign DNA in whole-genome sequences by looking for shifts in