2020

O'Brien et al. Domain-specific introduction to machine learning terminology, pitfalls and opportunities in CRISPR-based gene editing Briefings in Bioinformatics 2020 blog | press

2019

Bayat et al. BitEpi: A Fast and Accurate Exhaustive Higher-Order Epistasis Search BioRxiv 2019
Sathyanarayanan et al. A comparative study of multi-omics integration tools for cancer driver gene identification and tumour subtyping Briefings in Bioinformatics 2019
Bayat et al. VariantSpark, A Random Forest Machine Learning Implementation for Ultra High Dimensional Data BioRxiv 2019
Twine et al. TRIBES: A user-friendly pipeline for relatedness detection and disease gene discovery, BioArchive, 2019
Henden and Twine et al. IBD analysis of Australian amyotrophic lateral sclerosis SOD1-mutation carriers identifies five founder events and links sporadic cases to existing ALS families, BioArchive, 2019
Wilson et al. VARSCOT: variant-aware detection and scoring enables sensitive and personalized off-target detection for CRISPR-Cas9. BMC Biotechnology 2019 | blog
O'Brien et al. Unlocking HDR-mediated Nucleotide Editing by identifying high-efficiency target sites using machine learning Scientific Reports 2019 | blog | press

2018

Wilson et al. High Activity Target-Site Identification Using Phenotypic Independent CRISPR-Cas9 Core Functionality The CRISPR Journal 2018
Wilson et al. The current state and future of CRISPR-Cas9 gRNA design tools Frontiers in Pharmacology 2018

2015

O'Brien et al. VariantSpark: population scale clustering of genotype information BMC Genomics 2015

2014

O'Brien et al. GT-Scan: Identifying unique genomic targets Bioinformatics 2014