Scientific publication CSIRO co-leads the search for epistasis to reveal hidden secrets in our genome We co-led a consortium of international researchers in drafting a manifesto to uncover some of the unexplained features in our genome. Genetic epistasis refers to the changes in the effect on phenotype of
Dementia Discovering novel drivers of Alzheimer’s disease through genetic interactions Alzheimer’s disease is the most common form of dementia and predominantly affects people over 65 years old. Alzheimer’s disease is driven by multiple genetic and environmental influences, including complex interplay between
Scientific publication BitEpi, a software tool to find hidden epistatic interactions in the genome The Transformational Bioinformatics Group published BitEpi, a software tool to find the hidden gene-gene interactions in the genome. Complex diseases are driven my multiple genes and understanding this interplay could be the holy