CSIRO Bioinformatics


sparse.inv.cov is an R package designed for fitting large sparse covariance selection models. It is available under the General Public License and comes with absolutely no warranty.



The latest version of sparse.inv.cov is available for download as

Instructions for the installation of R packages can be found on the R Project website for Unix, Windows and Mac OS X.


To reproduce the fitted inverse covariance matrix in the BMC Bioinformatics paper – PDF.

A tutorial introducing the main functions of sparse.inv.cov and the typical work flow for an analysis – PDF.


For questions, comments and bug reports please contact Harri Kiiveri.